Enzymatic synthesis of N- epsilon -acyllysines

Montet Didier, Servat Françoise, Pina Michel, Graille Jean, Galzy Pierre, Arnaud Alain, Ledon H., Marcou Lucien. 1990. Enzymatic synthesis of N- epsilon -acyllysines. Journal of the American Oil Chemists' Society, 67 (1) : pp. 771-774.

Journal article ; Notoriété en attente de mise à jour
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Abstract : Chemical synthesis of N-epsilon-acyllysines on an industrial scale corresponds to new requirements in the surfactant field; only one chemical synthesis process is currently known for this type of molecule. A number of organic synthesis conducted in the laboratory so far have not made it possible to consider industrial development. However, biotechnologically, it has been shown that this molecule is easily accessible using a commercially available fixed lipase. Synthesis is caried out by causing a triglyceride to react with the lysine either with or without a solvent. The latter method gives the best results at the current stage of research. Given the availability of at least one fixed lipase on the market today, and the possibility of directly applying the reaction using oils, this reaction could be scaled up rapidly for industrial development. (Résumé d'auteur)

Mots-clés Agrovoc : Synthèse chimique, Amide, Acide gras, Lysine, Triglycéride, Estérase, Surfactant, Acylation

Mots-clés complémentaires : Synthèse enzymatique

Classification Agris : Q60 - Processing of non-food or non-feed agricultural products
Q02 - Food processing and preservation

Auteurs et affiliations

  • Montet Didier
  • Servat Françoise
  • Pina Michel
  • Graille Jean
  • Galzy Pierre
  • Arnaud Alain
  • Ledon H.
  • Marcou Lucien

Autres liens de la publication

  • Localisation du document : CD_PE188 [(Bibliothèque de Lavalette)]

Source : Cirad - Agritrop (

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