Vaccination against contagious bovine pleuropneumonia and the use of molecular tools in epidemiology

Thiaucourt François, Lorenzon Sophie, David Armelle, Tulasne Jean-Jacques, Domenech Joseph. 1998. Vaccination against contagious bovine pleuropneumonia and the use of molecular tools in epidemiology. Annals of the New York Academy of Sciences, 849 : pp. 146-151. Biennial Conference of the Society for Tropical Veterinary Medecine. 4, Montpellier, France, 5 May 1997/9 May 1997.

Journal article ; Article de revue à facteur d'impact
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Autre titre : La vaccination contre la péripneumonie contagieuse bovine et l'utilisation d'outils moléculaires en épidémiologie

Liste HCERES des revues (en SHS) : oui

Thème(s) HCERES des revues (en SHS) : Histoire et philosophie des sciences; Histoire, histoire de l'art, archéologie; Psychologie-éthologie-ergonomie

Abstract : Contagious bovine pleuropneumonia is a serious threat to cattle not only in Africa but also in southern Europe and possibly Asia. It is now present in countries that had been free of the disease for many years, giving rise to doubts about the efficiency of the control strategies. In Africa CBPP is controlled mainly by a vaccination policy that uses variant strains of Mycoplasma mycoides subsp mycoides biotype SC, called T1/44 or T1sr. Until recently, it was not possible to differentiate the various strains within the biotype and consequently to identify the vaccine strains. Restriction analysis of mycoplasma DNA with HindIII and Pst1 has been applied to 24 strains of African origin and one European strain. Each enzyme gave rise to different restriction profiles and the combination of the results permitted subdivision of these strains into 9 groups. Interestingly, some profiles of pathogenic strains seem to be restricted to certain geographical areas. The profile of the poorly immunogenic vaccinal strain KH3J is also very peculiar, and it is easily distinguished from that of the other vaccine strains originating from T1. This technique is simple once the strains are isolated. Efforts are now under way to use molecular tools based on PCR products to alleviate the difficulty of isolation. (Résumé d'auteur)

Mots-clés Agrovoc : Péripneumonie contagieuse bovine, Vaccination, Épidémiologie, Génétique moléculaire, Marqueur génétique, PCR, Mycoplasma mycoides

Mots-clés géographiques Agrovoc : Afrique, Asie, Europe

Classification Agris : L73 - Animal diseases

Auteurs et affiliations

  • Thiaucourt François, CIRAD-EMVT-SANTE ANIMALE (FRA)
  • Tulasne Jean-Jacques, CIRAD-EMVT-SANTE ANIMALE (FRA)
  • Domenech Joseph, CIRAD-EMVT-DIR (FRA)

Autres liens de la publication

  • Document en bibliothèque
  • Localisation du document : BA_L70 CAM 2405 [(Bibliothèque de Baillarguet)] ; BA_BR360 [(Bibliothèque de Baillarguet)]

Source : Cirad - Agritrop (

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