Contagious bovine pleuropneumonia. A reassessment of the efficacy of vaccines used in Africa

Thiaucourt François, YaYa Aboubakar, Wesonga Hezron, Huebschle O.J.B., Tulasne Jean-Jacques, Provost Alain. 2000. Contagious bovine pleuropneumonia. A reassessment of the efficacy of vaccines used in Africa. Annals of the New York Academy of Sciences, 916 : 71-80. Biennial Conference of the Society for Tropical Veterinary Medicine. 5, Key West, États-Unis, 12 Juin 1999/16 Juin 1999.

Liste HCERES des revues (en SHS) : oui

Thème(s) HCERES des revues (en SHS) : Histoire et philosophie des sciences; Histoire, histoire de l'art, archéologie; Psychologie-éthologie-ergonomie

Résumé : Contagious bovine pleuropneumonia is a major threat for cattle in Africa. Since 1956 the TI/44 strain has been used as a vaccine, and later on, T1sr, a streptomycin-resistant variant that gives fewer post-vaccinal reactions had been developed. These vaccines are known not to be very efficient but they normally should provide protection for about eight month. However, recent emergency vaccinations, performed in varions countries in the southern part of the continent apparently met with failure, casting doubts on the identity as well as the protection afforded by the Tlsr strain. A vaccine trial has been designed to reassess the real protection afforded by these vaccines in face of recently isolated pathogenic strains. Great care has been taken to test the original vaccinal strains at a dose corresponding to the minimum requirement by international standards. The test was perforned in Cameroon, Kenya, and Namibia as to take into account the genetic diversity that exists among the pathogenie strains. In those conditions, the protection rate at three months varied from 33 to 67%, whatever the strain used, TI/44 or T1sr. These results call for additional research for vaccine development and careful planning of strategies in the fight against CBPP.

Mots-clés Agrovoc : péripneumonie contagieuse bovine, Mycoplasma mycoides, vaccination, bovin

Mots-clés géographiques Agrovoc : Afrique au sud du Sahara

Classification Agris : L73 - Maladies des animaux

Auteurs et affiliations

• Thiaucourt François, CIRAD-EMVT-SANTE ANIMALE (FRA)
• YaYa Aboubakar, LANAVET (CMR)
• Wesonga Hezron, KARI (KEN)
• Huebschle O.J.B., CVL (NAM)
• Tulasne Jean-Jacques, CIRAD-EMVT-DIR (FRA)
• Provost Alain

Source : Cirad - Agritrop (https://agritrop.cirad.fr/477560/)

Métriques

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