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A quantitative trait locus analysis of natural genetic variation for Drosophila melanogaster oxidative stress survival

Wang Yue, Pot David, Kachman Stephen D., Nuzhdin Sergey V., Harshman Lawrence G.. 2006. A quantitative trait locus analysis of natural genetic variation for Drosophila melanogaster oxidative stress survival. Journal of Heredity, 97 (4) : pp. 355-366.

Journal article ; Article de revue à facteur d'impact
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Abstract : Little is known about natural genetic variation for survival under oxidative stress conditions or whether genetic variation for oxidative stress survival is associated with that for life-history traits. We have investigated survival in a high-oxygen environment at 2 adult densities using a set of recombinant inbred lines (RILs) isolated from a natural population of Drosophila melanogaster. Female and male oxidative stress survival was highly correlated. Quantitative trait loci (QTLs) for oxidative stress survival were identified on both autosomes. These QTLs were sometimes sex or density specific but were most often not. QTLs were identified that colocalize to the same region of the genome as longevity in other studies using the same set of RILs. We also determined early-age egg production and found QTLs for this trait, but there was no support for an association between oxidative stress survival and egg production. (Résumé d'auteur)

Mots-clés Agrovoc : Drosophila melanogaster, Oxydation, Stress, Variation génétique, Ovule, Analyse quantitative, Locus des caractères quantitatifs

Mots-clés complémentaires : QTL

Classification Agris : L50 - Animal physiology and biochemistry
L10 - Animal genetics and breeding

Champ stratégique Cirad : Hors axes (2005-2013)

Auteurs et affiliations

  • Wang Yue, University of Nebraska (USA)
  • Pot David, CIRAD-AMIS-UMR PIA (BRA) ORCID: 0000-0001-6144-8448
  • Kachman Stephen D., University of Nebraska (USA)
  • Nuzhdin Sergey V., UC (USA)
  • Harshman Lawrence G., University of Nebraska (USA)

Autres liens de la publication

Source : Cirad - Agritrop (https://agritrop.cirad.fr/533457/)

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