Renitelo cattle dermatophilosis and PCR-RFLP analysis of MHC gene

Razafindraibe Hanta, Raliniaina Modestine, Maillard Jean-Charles, Rakotondravao. 2006. Renitelo cattle dermatophilosis and PCR-RFLP analysis of MHC gene. Annals of the New York Academy of Sciences, 1081 : 489-491. Biennial Conference of the Society for Tropical Veterinary Medicine. 8, Hanoi, Viet Nam, 26 Juin 2005/1 Juillet 2005.

Liste HCERES des revues (en SHS) : oui

Thème(s) HCERES des revues (en SHS) : Histoire et philosophie des sciences; Histoire, histoire de l'art, archéologie; Psychologie-éthologie-ergonomie

Résumé : Renitelo breed is a cattle breed created at Kianjasoa station (Madagascar) by a triple crossing Malagasy Zebu x Limousine x Afrikander. This breed besides many valuable advantages, such as rapid growth and drought power, presents a huge disadvantage which is sensitivity to skin disease, dermatophilosis, previously known as streptotrichosis. This disease caused by Dermatophilus congolensis is one of the major threats for the population of Renitelo cattle. An allele of MHC gene has been shown to be dramatically associated to hypersensitivity to the disease in other cattle breed. To bring further information to tick borne disease clinical survey, mainly dermatophilosis, we wanted to verify if such allele could be found in this breed. Renitelo cattle included in this study were chosen for the presence of dermatophilosis lesions in more or less severe form (N = 17). These animals were blood sampled and a genetic analysis on the MHC gene BoLA-DRB3 was performed, by PCR amplification using BOD 31 & BOD 32 primers. Amplified products were analyzed by RFLP using enzymes. Restriction band profiles were characterized according to previously defined patterns. Three cows out of the 17 cattle analyzed for MHC gene presented the hypersensitive allele FDA. Two out of the three hypersensitive cows were pure breed while one was half breed. All the cows presented dermatophilosis lesions at least during rainy season but one of them particularly suffered from severe lesions covering all its body and died of the illness. This study shows that hypersensitivity allele found in other bovine breeds can be found in Renitelo breed. This result seemed to suggest that this characterization could be utilized in breeding program for this breed.

Classification Agris : L73 - Maladies des animaux

Champ stratégique Cirad : Axe 4 (2005-2013) - Santé animale et maladies émergentes

Auteurs et affiliations

• Razafindraibe Hanta, CENDRADERU (MDG)
• Raliniaina Modestine, CENDRADERU (MDG)
• Maillard Jean-Charles, CIRAD-EMVT-UPR Faune sauvage (VNM)
• Rakotondravao, CENDRADERU (MDG)

Source : Cirad - Agritrop (https://agritrop.cirad.fr/536150/)

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