Rodent-Borne Hantaviruses in Cambodia, Lao PDR, and Thailand

Blasdell Kim R., Cosson Jean François, Chaval Yannick, Herbreteau Vincent, Douangboupha Bounneuang, Jittapalapong Sathaporn, Lundqvist Ake, Hugot Jean-Pierre, Morand Serge, Buchy Philippe. 2011. Rodent-Borne Hantaviruses in Cambodia, Lao PDR, and Thailand. Ecohealth, 8 (4) : 432-443.

https://doi.org/10.1007/s10393-011-0725-7

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Quartile : Q2, Sujet : ENVIRONMENTAL SCIENCES

Résumé : In order to evaluate the circulation of hantaviruses present in southeast Asia, a large scale survey of small mammal species was carried out at seven main sites in the region (Cambodia, Lao People's Democratic Republic, and Thailand). Small scale opportunistic trapping was also performed at an eighth site (Cambodia). Using a standard IFA test, IgG antibodies reacting to Hantaan virus antigens were detected at six sites. Antibody prevalence at each site varied from 0 to 5.6% with antibodies detected in several rodent species (Bandicota indica, B. savilei, Maxomys surifer, Mus caroli, M. cookii, Rattus exulans, R. nitidius, R. norvegicus, and R. tanezumi). When site seroprevalence was compared with site species richness, seropositive animals were found more frequently at sites with lower species richness. In order to confirm which hantavirus species were present, a subset of samples was also subjected to RT-PCR. Hantaviral RNA was detected at a single site from each country. Sequencing confirmed the presence of two hantavirus species, Thailand and Seoul viruses, including one sample (from Lao PDR) representing a highly divergent strain of Seoul virus. This is the first molecular evidence of hantavirus in Lao PDR and the first reported L segment sequence data for Thailand virus.

Mots-clés Agrovoc : hantavirus, immunologie, Enquête pathologique, phylogénie, Rodentia

Mots-clés géographiques Agrovoc : Cambodge, République démocratique populaire lao, Thaïlande

Classification Agris : L73 - Maladies des animaux
L72 - Organismes nuisibles des animaux

Champ stratégique Cirad : Axe 4 (2005-2013) - Santé animale et maladies émergentes

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