Antifungal properties of lipophilized green coffee chlorogenic acid

Alonso Campos Angelina, Suárez-Quiroz Mirna, Valerio Alfaro Gerardo, Villeneuve Pierre, Figueroa-Espinoza Maria-Cruz, Gonzalez-Rios Oscar. 2013. Antifungal properties of lipophilized green coffee chlorogenic acid. In : Proceedings of the 24th International Conference on Coffee Science, San José, Costa Rica, 12th-16th November 2012 = Actes du 24ème Colloque scientifique international sur le café, San José, Costa Rica, 12-16 novembre 2012. ASIC. Paris : ASIC, pp. 380-384. ISBN 978-2-900212-23-3 International Conference on Coffee Science. 24, San José, Costa Rica, 11 November 2012/16 November 2012.

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Abstract : Chlorogenic acid (CGA) extracted from Mexican green coffee beans (Coffea arabica) was esterified to alcohols of different chain length (methanol, butanol, octanol, and dodecanol). CGA and lipophilized CGA (L-CGA) antifungal activities were tested on five toxigenic moulds from the Aspergillus genus (A. flavus, A. nomius, A. ochraceus, A. parasiticus, and A. westerdijkiae) using the microdilution method and the minimum inhibitory concentrations (MIC50 and MIC90) were determined. All molecules presented antifungal activity, however, only dodecyl chlorogenate and octyl chlorogenate showed a MIC50 for all fungi. Octyl chlorogenate had a MIC90 for A. flavus, A. parasiticus, and A. nomius. Lipophilization improves hydrophobicity of CGA resulting in amphiphilic molecules with antifungal properties. (Résumé d'auteur)

Classification Agris : Q04 - Food composition

Auteurs et affiliations

  • Alonso Campos Angelina, Instituto Tecnologico de Veracruz (MEX)
  • Suárez-Quiroz Mirna, Instituto Tecnologico de Veracruz (MEX)
  • Valerio Alfaro Gerardo, Instituto Tecnologico de Veracruz (MEX)
  • Villeneuve Pierre, CIRAD-PERSYST-UMR IATE (FRA) ORCID: 0000-0003-1685-1494
  • Figueroa-Espinoza Maria-Cruz, CIRAD-PERSYST-UMR IATE (FRA)
  • Gonzalez-Rios Oscar, Instituto Tecnologico de Veracruz (MEX)

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