Agritrop
Accueil

The genomic substrate for adaptive radiation in African cichlid fish

Brawand David, Wagner Catherine E., Li Yang I., Malinsky Milan, Keller Irène, Fan Shaohua, Simakov Oleg, Ng Alvin Y., Lim Zhi Wei, Bezault Etienne, Turner-Maier Jason, Johnson Jeremy, Alcazar Rosa, Noh Hyun Ji, Russell Pamela, Aken Bronwen, Alföldi Jessica, Amemiya Chris, Azzouzi Naoual, Baroiller Jean-François, Barloy-Hubler Frédérique, Berlin Aaron, Bloomquist Ryan, Carleton Karen L., Conte Matthew A., D'Cotta Helena, Eshel Orly, Gaffney Leslie, Galibert Francis, Gante Hugo F., Gnerre Sante, Greuter Lucie, Guyon Richard, Haddad Nathalie S., Haerty Wilfried, Harris Rayna M., Hofmann Hans A., Hourlier Thibaut, Hulata Gideon, Jaffe David B., Lara Marcia, Lee Alison P., MacCallum Iain, Mwaiko Salome, Nikaido Masato, Nishihara Hidenori, Ozouf-Costaz Catherine, Penman David, Przybylski Darius, Rakotomanga Michelle, Renn Suzy C. P., Ribeiro Filipe J., Ron Micha, Salzburger Walter, Sanchez-Pulido Luis, Santos Emilia, Searle Steve, Sharpe Ted, Swofford Ross, Tan Frederick J., Williams Louise, Young Sarah, Yin Shuangye, Okada Norihiro, Kocher Thomas D., Miska Eric A., Lander Eric S., Venkatesh Byrappa, Fernald Russell D., Meyer Axel, Ponting Chris P., Streelman J. Todd, Lindblad-Toh Kerstin, Seehausen Ole, Di Palma Frederica. 2014. The genomic substrate for adaptive radiation in African cichlid fish. Nature, 513 (7518) : 375-381.

Article de revue ; Article de revue à facteur d'impact
[img] Version publiée - Anglais
Accès réservé aux agents Cirad
Utilisation soumise à autorisation de l'auteur ou du Cirad.
document_574086.pdf

Télécharger (5MB)

Quartile : Outlier, Sujet : MULTIDISCIPLINARY SCIENCES

Liste HCERES des revues (en SHS) : oui

Thème(s) HCERES des revues (en SHS) : Economie-gestion; Psychologie-éthologie-ergonomie

Résumé : Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great Lakes of East Africa. To understand the molecular mechanisms underlying cichlid phenotypic diversity, we sequenced the genomes and transcriptomes of five lineages of African cichlids: the Nile tilapia (Oreochromis niloticus), an ancestral lineage with low diversity; and four members of the East African lineage: Neolamprologus brichardi/pulcher (older radiation, Lake Tanganyika), Metriaclima zebra (recent radiation, Lake Malawi), Pundamilia nyererei (very recent radiation, Lake Victoria), and Astatotilapia burtoni (riverine species around Lake Tanganyika). We found an excess of gene duplications in the East African lineage compared to tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs. In addition, we analysed sequence data from sixty individuals representing six closely related species from Lake Victoria, and show genome-wide diversifying selection on coding and regulatory variants, some of which were recruited from ancient polymorphisms. We conclude that a number of molecular mechanisms shaped East African cichlid genomes, and that amassing of standing variation during periods of relaxed purifying selection may have been important in facilitating subsequent evolutionary diversification. (Résumé d'auteur)

Mots-clés Agrovoc : Cichlidae, Oreochromis niloticus, Polymorphisme génétique, Génome, Phylogénie, Séquence nucléotidique, Génie génétique, Adaptation, Évolution, Lac, Cours d'eau

Mots-clés géographiques Agrovoc : Afrique orientale, Lac Victoria, Lac Tanganyika, Lac Nyasa

Mots-clés complémentaires : Pundamilia nyererei, Neolamprologus brichardi, Metriaclima zebra, Séquencage

Classification Agris : M01 - Pêche et aquaculture : considérations générales
L10 - Génétique et amélioration des animaux
L60 - Taxonomie et géographie animales

Axe stratégique Cirad : Axe 6 (2014-2018) - Sociétés, natures et territoires

Auteurs et affiliations

  • Brawand David, Broad Institute of MIT and Harvard (USA)
  • Wagner Catherine E., Swiss Federal Institute of Aquatic Science and Technology (CHE)
  • Li Yang I., University of Oxford (GBR)
  • Malinsky Milan, Wellcome Trust Sanger Institute (GBR)
  • Keller Irène, Swiss Federal Institute of Aquatic Science and Technology (CHE)
  • Fan Shaohua, University of Konstanz (DEU)
  • Simakov Oleg, University of Konstanz (DEU)
  • Ng Alvin Y., Institute of Molecular and Cell Biology (SGP)
  • Lim Zhi Wei, Institute of Molecular and Cell Biology (SGP)
  • Bezault Etienne, Reed College (USA)
  • Turner-Maier Jason, Broad Institute of MIT and Harvard (USA)
  • Johnson Jeremy, Broad Institute of MIT and Harvard (USA)
  • Alcazar Rosa, Stanford University (USA)
  • Noh Hyun Ji, Broad Institute of MIT and Harvard (USA)
  • Russell Pamela, California Institute of Technology (USA)
  • Aken Bronwen, Wellcome Trust Sanger Institute (GBR)
  • Alföldi Jessica, Broad Institute of MIT and Harvard (USA)
  • Amemiya Chris, Benaroya Research Institute at Virginia Mason (USA)
  • Azzouzi Naoual, Université de Rennes I (FRA)
  • Baroiller Jean-François, CIRAD-PERSYST-UMR INTREPID (FRA) ORCID: 0000-0002-0992-1725
  • Barloy-Hubler Frédérique, Université de Rennes I (FRA)
  • Berlin Aaron, Broad Institute of MIT and Harvard (USA)
  • Bloomquist Ryan, Georgia Institute of Technology (USA)
  • Carleton Karen L., University of Maryland (USA)
  • Conte Matthew A., University of Maryland (USA)
  • D'Cotta Helena, CIRAD-PERSYST-UMR INTREPID (FRA)
  • Eshel Orly, Volcani Center (ISR)
  • Gaffney Leslie, Broad Institute of MIT and Harvard (USA)
  • Galibert Francis, Université de Rennes I (FRA)
  • Gante Hugo F., University of Basel (CHE)
  • Gnerre Sante, Broad Institute of MIT and Harvard (USA)
  • Greuter Lucie, Swiss Federal Institute of Aquatic Science and Technology (CHE)
  • Guyon Richard, Université de Rennes I (FRA)
  • Haddad Nathalie S., Georgia Institute of Technology (USA)
  • Haerty Wilfried, University of Oxford (GBR)
  • Harris Rayna M., University of Texas (USA)
  • Hofmann Hans A., University of Texas (USA)
  • Hourlier Thibaut, Wellcome Trust Sanger Institute (GBR)
  • Hulata Gideon, Volcani Center (ISR)
  • Jaffe David B., Broad Institute of MIT and Harvard (USA)
  • Lara Marcia, Broad Institute of MIT and Harvard (USA)
  • Lee Alison P., Institute of Molecular and Cell Biology (SGP)
  • MacCallum Iain, Broad Institute of MIT and Harvard (USA)
  • Mwaiko Salome, Swiss Federal Institute of Aquatic Science and Technology (CHE)
  • Nikaido Masato, Tokyo Institute of Technology (JPN)
  • Nishihara Hidenori, Tokyo Institute of Technology (JPN)
  • Ozouf-Costaz Catherine, MNHN (FRA)
  • Penman David, University of Stirling (GBR)
  • Przybylski Darius, Broad Institute of MIT and Harvard (USA)
  • Rakotomanga Michelle, Université de Rennes I (FRA)
  • Renn Suzy C. P., Reed College (USA)
  • Ribeiro Filipe J., Broad Institute of MIT and Harvard (USA)
  • Ron Micha, Volcani Center (ISR)
  • Salzburger Walter, University of Basel (CHE)
  • Sanchez-Pulido Luis, University of Oxford (GBR)
  • Santos Emilia, University of Basel (CHE)
  • Searle Steve, Wellcome Trust Sanger Institute (GBR)
  • Sharpe Ted, Broad Institute of MIT and Harvard (USA)
  • Swofford Ross, Broad Institute of MIT and Harvard (USA)
  • Tan Frederick J., Carnegie Institution of Washington (USA)
  • Williams Louise, Broad Institute of MIT and Harvard (USA)
  • Young Sarah, Broad Institute of MIT and Harvard (USA)
  • Yin Shuangye, Broad Institute of MIT and Harvard (USA)
  • Okada Norihiro, Tokyo Institute of Technology (JPN)
  • Kocher Thomas D., University of Maryland (USA)
  • Miska Eric A., Gurdon Institute (USA)
  • Lander Eric S., Broad Institute of MIT and Harvard (USA)
  • Venkatesh Byrappa, Institute of Molecular and Cell Biology (SGP)
  • Fernald Russell D., Stanford University (USA)
  • Meyer Axel, University of Konstanz (DEU)
  • Ponting Chris P., University of Oxford (GBR)
  • Streelman J. Todd, Georgia Institute of Technology (USA)
  • Lindblad-Toh Kerstin, Broad Institute of MIT and Harvard (USA)
  • Seehausen Ole, Swiss Federal Institute of Aquatic Science and Technology (CHE)
  • Di Palma Frederica, Broad Institute of MIT and Harvard (USA)

Source : Cirad - Agritrop (https://agritrop.cirad.fr/574086/)

Voir la notice (accès réservé à la Dist) Voir la notice (accès réservé à la Dist)

[ Page générée et mise en cache le 2019-01-16 ]