Agritrop
Home

Hypoglycaemic, hypolipidaemic and antioxidant effects of blackberry beverage consumption in streptozotocin-induced diabetic rats

Azofeifa Gabriela, Quesada Silvia, Navarro Laura, Hidalgo Olman, Portet Karine, Pérez Ana Mercedes, Vaillant Fabrice, Poucheret Patrick, Michel Alain. 2016. Hypoglycaemic, hypolipidaemic and antioxidant effects of blackberry beverage consumption in streptozotocin-induced diabetic rats. Journal of Functional Foods, 26 : pp. 330-337.

Journal article ; Article de revue à facteur d'impact
[img] Published version - Anglais
Access restricted to CIRAD agents
Use under authorization by the author or CIRAD.
1-s2.0-S1756464616302158-main.pdf

Télécharger (563kB) | Request a copy

Quartile : Q1, Sujet : FOOD SCIENCE & TECHNOLOGY

Abstract : Abnormal glucose metabolism, hyperlipidaemia profiles and high levels of radical oxygen species (ROS) are classic features of diabetes. This study evaluates the effect of the consumption of two different blackberry beverages at 25 and 12.5% given orally for 40 days to rats with streptozotocin induced diabetes. The lower dose of blackberry (12.5%) non-statistically decreased glycaemia (−10.4%), triacylglycerols (−4.6%) and cholesterol (−21.0%). These differences were not statistically significant. The higher dose of blackberry (25%) significantly decreased glucose (−48.6%), triacylglycerols (−43.5%) and cholesterol (−28.6%). The higher dose of blackberry (25%) improved plasma antioxidant capacity, reduced the levels of lipid peroxidation in plasma (−19%) and in kidney (−23%). Blackberry intake did not improve catalase, suggesting that attenuation of oxidative stress via scavenging activities rather than improving the activities of antioxidant enzymes. These results provide promising data for this blackberry as a dietary adjuvant to the pharmacological management of diabetes. (Résumé d'auteur)

Classification Agris : Q04 - Food composition
L51 - Animal physiology - Nutrition
L70 - Veterinary science and hygiene

Champ stratégique Cirad : Axe 3 (2014-2018) - Alimentation durable

Auteurs et affiliations

  • Azofeifa Gabriela, UCR (CRI)
  • Quesada Silvia, UCR (CRI)
  • Navarro Laura, UCR (CRI)
  • Hidalgo Olman, Université de Montpellier (FRA)
  • Portet Karine, UM1 (FRA)
  • Pérez Ana Mercedes, UCR (CRI)
  • Vaillant Fabrice, CIRAD-PERSYST-UMR Qualisud (COL) ORCID: 0000-0001-6318-1353
  • Poucheret Patrick, UM1 (FRA)
  • Michel Alain, UM1 (FRA)

Source : Cirad-Agritrop (https://agritrop.cirad.fr/583640/)

View Item (staff only) View Item (staff only)

[ Page générée et mise en cache le 2020-10-30 ]