Geographic variations of the bird-borne structural risk of West Nile virus circulation in Europe

Durand Benoit, Tran Annelise, Balança Gilles, Chevalier Véronique. 2017. Geographic variations of the bird-borne structural risk of West Nile virus circulation in Europe. PloS One, 12 (10):e0185962, 15 p.

Journal article ; Article de recherche ; Article de revue à facteur d'impact Revue en libre accès total
Published version - Anglais
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Thème(s) HCERES des revues (en SHS) : Psychologie-éthologie-ergonomie; Staps

Abstract : The structural risk of West Nile Disease results from the usual functioning of the socio-ecological system, which may favour the introduction of the pathogen, its circulation and the occurrence of disease cases. Its geographic variations result from the local interactions between three components: (i) reservoir hosts, (ii) vectors, both characterized by their diversity, abundance and competence, (iii) and the socio-economic context that impacts the exposure of human to infectious bites. We developed a model of bird-borne structural risk of West Nile Virus (WNV) circulation in Europe, and analysed the association between the geographic variations of this risk and the occurrence of WND human cases between 2002 and 2014. A meta-analysis of WNV serosurveys conducted in wild bird populations was performed to elaborate a model of WNV seropositivity in European bird species, considered a proxy for bird exposure to WNV. Several eco-ethological traits of bird species were linked to seropositivity and the statistical model adequately fitted species-specific seropositivity data (area under the ROC curve: 0.85). Combined with species distribution maps, this model allowed deriving geographic variations of the bird-borne structural risk of WNV circulation. The association between this risk, and the occurrence of WND human cases across the European Union was assessed. Geographic risk variations of bird-borne structural risk allowed predicting WND case occurrence in administrative districts of the EU with a sensitivity of 86% (95% CI: 0.79–0.92), and a specificity of 68% (95% CI: 0.66–0.71). Disentangling structural and conjectural health risks is important for public health managers as risk mitigation procedures differ according to risk type. The results obtained show promise for the prevention of WND in Europe. Combined with analyses of vector-borne structural risk, they should allow designing efficient and targeted prevention measures.

Mots-clés géographiques Agrovoc : Europe

Mots-clés libres : West Nile, Europe, Spatial modelling, Geographic Information System

Classification Agris : L73 - Animal diseases
000 - Autres thèmes
U10 - Mathematical and statistical methods

Champ stratégique Cirad : Axe 4 (2014-2018) - Santé des animaux et des plantes

Auteurs et affiliations

  • Durand Benoit, ANSES (FRA)
  • Tran Annelise, CIRAD-ES-UMR TETIS (REU) ORCID: 0000-0001-5463-332X
  • Balança Gilles, CIRAD-BIOS-UMR ASTRE (FRA)
  • Chevalier Véronique, CIRAD-BIOS-UMR ASTRE (KHM) - auteur correspondant

Source : Cirad-Agritrop (

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