Building global genomics initiatives and enabling data sharing: Insights from multiple case studies

Fusi Federica, Manzella Daniele, Louafi Selim, Welch Eric W.. 2018. Building global genomics initiatives and enabling data sharing: Insights from multiple case studies. OMICS - A Journal of Integrative Biology, 22 (4) : pp. 237-247.

Journal article ; Article de recherche ; Article de revue à facteur d'impact
Published version - Anglais
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Abstract : This genomics global governance research study presents the dynamics and the evolving nature of salient challenges that global genomics initiatives encounter in designing new models for data management, exchange, and collaboration across disciplines, sectors, and countries. Using a multiple case study approach, we assessed and compared organizational responses across diverse genomics initiatives. The richness of a comparative qualitative analysis clearly shows the complexity addressed by genomics initiatives and, importantly, expands current studies by moving beyond an open versus property regime dichotomy. Although we identify some common themes, fundamental differences emerge in the way genomics initiatives set goals, manage heterogeneity, define resources, devise governance, and enable data sharing. Such differences demonstrate the ongoing processes of adapting governance structures, management processes, and organizational design solutions that are implemented in response to different social, technical, and policy environments. We find that genomics initiatives largely benefit from and are shaped by the engagement with large communities of scientists to rethink and design shared rules and guidelines for data exchange and use. Our study provides direct guidance to future global genomics initiatives, but it also offers a benchmark for research in the omics field broadly, both in terms of design and methodological approaches to understand the emerging forms of scientific governance and innovation ecosystems.

Mots-clés libres : Global genomics initiatives, Organizational design, Data sharing, Case study, Global governance innovation

Classification Agris : U10 - Computer science, mathematics and statistics
000 - Other themes
F30 - Plant genetics and breeding
L10 - Animal genetics and breeding

Champ stratégique Cirad : Axe 1 (2014-2018) - Agriculture écologiquement intensive

Agence(s) de financement européenne(s) : European Commission

Programme de financement européen : FP7

Projet(s) de financement européen(s) : Global challenges and bio-based economy: Assessing institutional structures, constraints and outcomes of bio-based research in Agriculture

Auteurs et affiliations

  • Fusi Federica, Arizona State University (USA) - auteur correspondant
  • Manzella Daniele, Arizona State University (USA)
  • Louafi Selim, CIRAD-BIOS-UMR AGAP (FRA)
  • Welch Eric W., Arizona State University (USA)

Source : Cirad-Agritrop (

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