Seawater and freshwater challenges affect the insulin-like growth factors IGF-I and IGF-II in liver and osmoregulatory organs of the tilapia

Link Karl, Berishvili Giorgi, Shved Natallia, D'Cotta Helena, Baroiller Jean-François, Reinecke Manfred, Eppler Elisabeth. 2010. Seawater and freshwater challenges affect the insulin-like growth factors IGF-I and IGF-II in liver and osmoregulatory organs of the tilapia. Molecular and Cellular Endocrinology, 327 (1-2) : 40-46.

Quartile : Q2, Sujet : ENDOCRINOLOGY & METABOLISM / Quartile : Q2, Sujet : CELL BIOLOGY

Résumé : Contradictory studies suggest IGF-I in fish liver and gills is involved in osmoregulation, but nothing is known about the kidney and intestine's role nor about IGF-II's role in any organ. Tilapia were transferred from freshwater (FW) to seawater (SW) for 1 week (wk) and retransferred to FW for another week. At 4 h, 1 d, 2 d, 3 d and 1wk after SW-transfer and FW-retransfer IGF-I, IGF-II and growth hormone receptor (GHR1) mRNA were measured by real-time PCR. Hepatic IGF-I, IGF-II and GHR1 mRNA were downregulated in parallel after SW-transfer, recovered and were again downregulated after FWretransfer. In gills, IGF-I, IGF-II andGHR1were upregulated synchronously after SW-transfer and, partially also after FW-retransfer. The renal genes were downregulated after SW-transfer and partially upregulated after FW-retransfer. Persisting upregulation in intestinal IGF-I mRNA occurred after FW-retransfer. Thus, endocrine and auto/paracrine IGF-I and IGF-II seem to be involved in fish osmoregulation in an organ-specific manner. =

Mots-clés Agrovoc : Sarotherodon melanotheron, adaptation, gène, facteur de croissance igf, insuline, salinité, endocrinologie, eau de mer, eau douce, foie, intestin, osmorégulation

Mots-clés géographiques Agrovoc : Afrique occidentale

Classification Agris : L52 - Physiologie animale - Croissance et développement
M12 - Production de l'aquaculture

Champ stratégique Cirad : Axe 1 (2005-2013) - Intensification écologique

Auteurs et affiliations

• Link Karl, Institute of Anatomy (CHE)
• Berishvili Giorgi, Institute of Anatomy (CHE)
• Shved Natallia, Institute of Anatomy (CHE)
• D'Cotta Helena, CIRAD-PERSYST-UPR Aquaculture (FRA) ORCID: 0000-0003-2739-3476
• Baroiller Jean-François, CIRAD-PERSYST-UPR Aquaculture (FRA) ORCID: 0000-0002-0992-1725
• Reinecke Manfred, Institute of Anatomy (CHE)
• Eppler Elisabeth, Institute of Anatomy (CHE)

Source : Cirad - Agritrop (https://agritrop.cirad.fr/556388/)

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