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Métagénomique virale et pathologie Une histoire récente

Bernardo Pauline, Albina Emmanuel, Eloit Marc, Roumagnac Philippe. 2013. Métagénomique virale et pathologie Une histoire récente. MS - Médecine Sciences, 29 (5) : pp. 501-508.

Journal article ; Article de revue à facteur d'impact
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Titre anglais : Pathology and viral metagenomics, a recent history

Quartile : Q4, Sujet : MEDICINE, RESEARCH & EXPERIMENTAL

Liste HCERES des revues (en SHS) : oui

Thème(s) HCERES des revues (en SHS) : Psychologie-éthologie-ergonomie

Abstract : Human, animal and plant viral diseases have greatly benefited from recent metagenomics developments. Viral metagenomics is a cultureindependent approach used to investigate the complete viral genetic populations of a sample. During the last decade, metagenomics concepts and techniques that were first used by ecologists progressively spread into the scientific field of viral pathology. The sample, which was first for ecologists a fraction of ecosystem, became for pathologists an organism that hosts millions of microbes and viruses. This new approach, providing without a priori high resolution qualitative and quantitative data on the viral diversity, is now revolutionizing the way pathologists decipher viral diseases. This review describes the very last improvements of the high throughput next generation sequencing methods and discusses the applications of viral metagenomics in viral pathology, including discovery of novel viruses, viral surveillance and diagnostic, large-scale molecular epidemiology, and viral evolution. (Résumé d'auteur)

Mots-clés Agrovoc : Génie génétique, Virologie, Séquence nucléotidique, Écologie microbienne, Écosystème, Virose, Virus, Génétique des populations, Maladie des animaux, Maladie de l'homme, Maladie des plantes

Mots-clés complémentaires : Séquencage

Classification Agris : H20 - Plant diseases
L73 - Animal diseases
000 - Other themes
U30 - Research methods

Champ stratégique Cirad : Axe 4 (2005-2013) - Santé animale et maladies émergentes

Auteurs et affiliations

  • Bernardo Pauline, CIRAD-BIOS-UMR BGPI (FRA)
  • Albina Emmanuel, CIRAD-BIOS-UMR CMAEE (GLP)
  • Eloit Marc, Institut Pasteur (FRA)
  • Roumagnac Philippe, CIRAD-BIOS-UMR BGPI (FRA) ORCID: 0000-0001-5002-6039

Source : Cirad - Agritrop (https://agritrop.cirad.fr/569246/)

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