Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar

Porphyre Vincent, Rakotoharinome Vincent Michel, Randriamparany Tantely, Pognon Damien, Prévost Stéphanie, Le Bizec Bruno. 2013. Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar. Food Additives and Contaminants. Part A. Chemistry, Analysis, Control, Exposure and Risk Assessment, 30 (12) : pp. 2108-2113.

Journal article ; Article de revue à facteur d'impact
[img] Published version - Anglais
Access restricted to CIRAD agents
Use under authorization by the author or CIRAD.

Télécharger (366kB)

Quartile : Q1, Sujet : FOOD SCIENCE & TECHNOLOGY / Quartile : Q1, Sujet : CHEMISTRY, APPLIED / Quartile : Q3, Sujet : TOXICOLOGY

Abstract : In Madagascar, little information about drug residues in animal products is available. However, recently, official veterinary services were informed about the misuse of human injectable contraceptives in pig farms as an alternative for chirurgical castration of adult sows before culling. We investigated pigs (n = 80) slaughtered in 7 Malagasy abattoirs and raised in 8 of the 22 Malagasy regions (1) to confirm the contamination of carcasses by anabolic hormones by using LC-MS/MS, (2) to identify the substances of concern and (3) to explore the consumers' exposure to hormone residues. Medroxyprogesterone acetate was the only synthetic hormone detected in kidney fat. Samples positive with medroxyprogesterone acetate were observed in 66.7% of the districts investigated and in 87.5% of the surveyed regions, confirming its large misuse in livestock. Public awareness campaigns and control improvement among the animal production sector and among the Malagasy public health sector are therefore urgent. (Résumé d'auteur)

Mots-clés Agrovoc : Contamination chimique, Viande porcine, Produit carné, Hormone, Contraceptif, Résidu de médicament

Mots-clés géographiques Agrovoc : Madagascar

Classification Agris : Q03 - Food contamination
L53 - Animal physiology - Reproduction
L70 - Veterinary science and hygiene - General aspects

Champ stratégique Cirad : Axe 3 (2005-2013) - Alimentation accessible et de qualité

Auteurs et affiliations

  • Porphyre Vincent, CIRAD-ES-UMR SELMET (REU) ORCID: 0000-0002-5561-2667
  • Rakotoharinome Vincent Michel, Ministère de l'élevage (Madagascar) (MDG)
  • Randriamparany Tantely, LNDV (MDG)
  • Pognon Damien, CIRAD-ES-UMR SELMET (REU)
  • Prévost Stéphanie, ONIRIS (FRA)
  • Le Bizec Bruno, ONIRIS (FRA)

Source : Cirad - Agritrop (

View Item (staff only) View Item (staff only)

[ Page générée et mise en cache le 2021-05-17 ]