Molecular evolution of peste des petits ruminants virus

Muniraju Murali, Munir Muhammad, Parthiban AravindhBabu R., Banyard Ashley C., Bao Jingyue, Wang Zhiliang, Ayebazibwe Chrisostom, Ayelet Gelagay, El Harrak Mehdi, Mahapatra Mana, Libeau Geneviève, Batten Carrie, Parida Satya. 2014. Molecular evolution of peste des petits ruminants virus. Emerging Infectious Diseases, 20 (12) : 2023-2033.

Quartile : Q1, Sujet : INFECTIOUS DISEASES / Quartile : Q1, Sujet : IMMUNOLOGY

Résumé : Despite safe and efficacious vaccines against peste des petits ruminants virus (PPRV), this virus has emerged as the cause of a highly contagious disease with serious economic consequences for small ruminant agriculture across Asia, the Middle East, and Africa. We used complete and partial genome sequences of all 4 lineages of the virus to investigate evolutionary and epidemiologic dynamics of PPRV. A Bayesian phylogenetic analysis of all PPRV lineages mapped the time to most recent common ancestor and initial divergence of PPRV to a lineage III isolate at the beginning of 20th century. A phylogeographic approach estimated the probability for root location of an ancestral PPRV and individual lineages as being Nigeria for PPRV, Senegal for lineage I, Nigeria/Ghana for lineage II, Sudan for lineage III, and India for lineage IV. Substitution rates are critical parameters for understanding virus evolution because restrictions in genetic variation can lead to lower adaptability and pathogenicity.

Mots-clés Agrovoc : peste des petits ruminants, virus peste petits ruminants, évolution, biologie moléculaire, virologie, épidémiologie, séquence nucléotidique, vaccin

Mots-clés géographiques Agrovoc : Israël, Éthiopie, Kenya, Ghana, Nigéria, Oman, Soudan, Arabie Saoudite, Sénégal, Tchad, Inde, Côte d'Ivoire, Türkiye, Émirats arabes unis, Bénin, Ouganda, Chine, Maroc, Pakistan, Togo, Jordanie, Asie, Proche-Orient, Afrique

Classification Agris : L73 - Maladies des animaux

Champ stratégique Cirad : Axe 4 (2014-2018) - Santé des animaux et des plantes

Auteurs et affiliations

• Muniraju Murali, The Pirbright Institute (GBR)
• Munir Muhammad, Swedish University of Agricultural Sciences (SWE)
• Parthiban AravindhBabu R., The Pirbright Institute (GBR)
• Banyard Ashley C., AHVLA (GBR)
• Bao Jingyue, China Animal Health and Epidemiology Centre (CHN)
• Wang Zhiliang, China Animal Health and Epidemiology Centre (CHN)
• Ayebazibwe Chrisostom, National Animal Disease Diagnostics and Epidemiology Centre (UGA)
• Ayelet Gelagay, NVI (ETH)
• El Harrak Mehdi, Biopharma (MAR)
• Mahapatra Mana, The Pirbright Institute (GBR)
• Libeau Geneviève, CIRAD-BIOS-UMR CMAEE (FRA)
• Batten Carrie, The Pirbright Institute (GBR)
• Parida Satya, Institute for Animal Health (GBR)

Source : Cirad - Agritrop (https://agritrop.cirad.fr/574439/)

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