Alphacoronaviruses detected in French bats are phylogeographically linked to coronaviruses of European bats

Goffard Anne, Demanche Christine, Arthur Laurent, Pinçon Claire, Michaux Johan, Dubuisson Jean. 2015. Alphacoronaviruses detected in French bats are phylogeographically linked to coronaviruses of European bats. Viruses, 7 (12) : pp. 6279-6290.

Journal article ; Article de recherche ; Article de revue à facteur d'impact Revue en libre accès total
Published version - Anglais
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Quartile : Q2, Sujet : VIROLOGY

Abstract : Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for the first time the presence of alpha-CoVs in French Pipistrellus pipistrellus bat species with an estimated prevalence of 4.2%. Based on the analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) gene, phylogenetic analyses show that alpha-CoVs sequences detected in French bats are closely related to other European bat alpha-CoVs. Phylogeographic analyses of RdRp sequences show that several CoVs strains circulate in European bats: (i) old strains detected that have probably diverged a long time ago and are detected in different bat subspecies; (ii) strains detected in Myotis and Pipistrellus bat species that have more recently diverged. Our findings support previous observations describing the complexity of the detected CoVs in bats worldwide. (Résumé d'auteur)

Mots-clés Agrovoc : Coronavirinae, Coronaviridae, Phylogénie, Chiroptera, Distribution géographique, Transmission des maladies, Hôte, Identification, Biologie moléculaire, Alphacoronavirus

Mots-clés géographiques Agrovoc : France, Europe

Mots-clés complémentaires : Pipistrellus pipistrellus, Myotis myotis, Barbastella barbastellus, Eptesicus serotinus

Classification Agris : L73 - Animal diseases
L72 - Pests of animals
L60 - Animal taxonomy and geography

Champ stratégique Cirad : Axe 4 (2014-2018) - Santé des animaux et des plantes

Auteurs et affiliations

  • Goffard Anne, Université de Lille (FRA)
  • Demanche Christine, Université de Lille (FRA)
  • Arthur Laurent, Museum d'Histoire Naturel de Bourges (FRA)
  • Pinçon Claire, Université de Lille (FRA)
  • Michaux Johan, CIRAD-ES-UPR AGIRs (FRA)
  • Dubuisson Jean, Université de Lille (FRA)

Source : Cirad-Agritrop (

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