Comparison between comparative tuberculin and y-interferon tests for the diagnosis of bovine tuberculosis in Ethiopia

Ameni Gobena, Mshana R.N., Miorner Hakan, Roger François, Tibbo Markos. 1999. Comparison between comparative tuberculin and y-interferon tests for the diagnosis of bovine tuberculosis in Ethiopia. Journal of the Ethiopian Veterinary Association, 3 (1) : 46-59.

Autre titre : Comparaison entre les tests à partir de tuberculine et interferon gamma pour le diagnostic de la tuberculose bovine en Ethiopie

Résumé : A study to determine and compare the sensitivities and specificities of comparative cervical tuberculin and gamma interferon tests for the diagnosis of bovine tuberculosis was conducted on 30 zebu oxen. The results of the tests were compared with that of acid fast bacilli found by bacteriological culturing and histopathological examinations. The sensitivity and specificity of comparative cervical tuberculin test were found to be 90.9% and 99.9%, respectively. Those of commercial gamma interferon test were determined to be 95.5% and 87.7%, respectively. No significant differences were found between sensitivities (Yates' corrected X2 = 0.32; p = 0.57) and specificities (Yates' corrected X2 = 2.54; p = 0.11) of the two tests. Furthermore, strong positive correlation (r = 0.76) was recorded between change in skin thickness to bovine PPD injection and optical density in the bovine PPD interferon gamma assay. On the other hand, the correlation (r = 0.47) between change in skin thickness to injection of avian PPD and optical density in avian PPD interferon gamma assay was found to be relatively weaker. Therefore, on the basis of this preliminary investigation, it can be concluded that the choice between the two tests depends on the economic standard, livestock management system, simplicity and time factor rather than diagnostic value.

Mots-clés Agrovoc : tuberculose, bovin, diagnostic, zoonose, interféron, zébu, test biologique, densité, immunisation

Mots-clés géographiques Agrovoc : Éthiopie

Classification Agris : L73 - Maladies des animaux

Auteurs et affiliations

• Ameni Gobena
• Mshana R.N.
• Miorner Hakan
• Roger François, CIRAD-EMVT-SANTE ANIMALE (MDG) ORCID: 0000-0002-1573-6833
• Tibbo Markos

Source : Cirad - Agritrop (https://agritrop.cirad.fr/401320/)

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