Hev b 1, Hev b 2 and Hev b 3 content in natural rubber latex and latex gloves

Yeang Hoong Yeet, Lau C.H., Arif S.A.M., Loke Y.H., Chan J.L., Hamzah S., Hamilton R.G.. 2001. Hev b 1, Hev b 2 and Hev b 3 content in natural rubber latex and latex gloves. In : Biotechnology and rubber tree : Proceedings of IRRDB symposium, 25-28 September 2001, Montpellier, France. Sainte-Beuve Jérôme (ed.). IRRDB, CIRAD-CP-HEVEA. Montpellier : CIRAD IRRDB Symposium, Montpellier, France, 25 Septembre 2001/28 Septembre 2001.

Résumé : Contact with latex gloves or powder from the gloves can induce an allergic reaction in sensitized persons. Although eleven latex allergens (Hev b 1 to Hev b 11) have been identified, there have been few reports on the levels of the specific allergens present in latex gloves. A study was carried out to compare the contents of three latex allergens, Hev b 1, Hev b 2 and Hev b 3 in latex examination gloves and in fresh natural rubber latex. Hev b 2 is a soluble protein located in latex organelles called lutoids1, whereas Hev b 1 and Hev b 3 are insoluble proteins located on the surface of the rubber particles2. Hev b 3 is slightly solubilized when the latex is ammoniated for glove manufacture3, and this property is similarly expected of Hev b 1.

Auteurs et affiliations

• Yeang Hoong Yeet, MRB (MYS)
• Lau C.H., MRB (MYS)
• Arif S.A.M., MRB (MYS)
• Loke Y.H., MRB (MYS)
• Chan J.L., MRB (MYS)
• Hamzah S., MRB (MYS)
• Hamilton R.G., Université John Hopkins (USA)

Source : Cirad - Agritrop (https://agritrop.cirad.fr/513752/)

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