Pathology and viral metagenomics, a recent history

Bernardo Pauline, Fernandez Emmanuel, Filloux Denis, Albina Emmanuel, Eloit Marc, Roumagnac Philippe. 2013. Pathology and viral metagenomics, a recent history. In : 14èmes Rencontres de virologie végétale (RVV 2013) : Aussois, France, 13-17 janvier 2013. Marais Armelle (ed.), Revers Frédéric (ed.). SFP, INRA. Paris : SFP, Résumé, 20. Rencontres de Virologie Végétale. 14, Aussois, France, 13 Janvier 2013/17 Janvier 2013.

Résumé : Human, animal and plant viral pathologies have greatly benefited from recent metagenomics development. Viral metagenomics is a culture-independent approach used to investigate the complete viral genetic populations of a sample. The last decade, metagenomics concepts and techniques that were first used by ecologists, progressively spread into the scientific field of viral pathology. The sample, which has been a fraction of ecosystems for ecologists, became for pathologists organisms that host millions of microbes and viruses. This new approach, providing without a priori high-resolution qualitative and quantitative data on the viral diversity, is now revolutionizing the way pathologists decipher viral diseases. This review describes the very last improvements of the high throughput next generation sequencing methods and discusses the applications of viral metagenomics in viral pathology, including discovery of novel viruses, viral surveillance and diagnostic, large-scale molecular epidemiology, and viral evolution. (Texte intégral)

Classification Agris : H20 - Maladies des plantes

Auteurs et affiliations

• Bernardo Pauline, CIRAD-BIOS-UMR BGPI (FRA)
• Fernandez Emmanuel, CIRAD-BIOS-UMR BGPI (FRA)
• Filloux Denis, CIRAD-BIOS-UMR BGPI (FRA)
• Albina Emmanuel, CIRAD-BIOS-UMR CMAEE (GLP)
• Eloit Marc, Institut Pasteur (FRA)
• Roumagnac Philippe, CIRAD-BIOS-UMR BGPI (FRA) ORCID: 0000-0001-5002-6039

Source : Cirad - Agritrop (https://agritrop.cirad.fr/568021/)

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