Trypa-NO! contributes to the elimination of gambiense human African trypanosomiasis by combining tsetse control with "screen, diagnose and treat" using innovative tools and strategies

Ndung'u Joseph Mathu, Boulangé Alain, Picado Albert, Mugenyi Albert, Mortensen Allan, Hope Andrew, Guihini Mollo Brahim, Bucheton Bruno, Wamboga Charles, Waiswa Charles, Kaba Dramane, Matovu Enock, Courtin Fabrice, Garrod Gala, Gimonneau Geoffrey, Bingham Georgina V., Mahamat Hassane Hassane, Tirados Inaki, Saldanha Isabel, Kaboré Jacques, et al.. 2020. Trypa-NO! contributes to the elimination of gambiense human African trypanosomiasis by combining tsetse control with "screen, diagnose and treat" using innovative tools and strategies. PLoS Neglected Tropical Diseases, 14 (11):e0008738, 9 p.

Quartile : Q1, Sujet : PARASITOLOGY / Quartile : Q1, Sujet : TROPICAL MEDICINE

Résumé : Gambiense human African trypanosomiasis (g-HAT) is the chronic form of sleeping sickness caused by Trypanosoma brucei gambiense in West and Central Africa, while Trypanosoma bru- cei rhodesiense causes an acute form in eastern Africa. g-HAT is targeted for elimination as a public health problem by 2020 and 0 transmission by 2030. Control of g-HAT is largely based on identification and treatment of infected individuals, supplemented by control of the tsetse fly vectors. There has been growing evidence that when both tsetse control and case identification activities are carried out simultaneously in the same geographies, elimination of the disease is accelerated. Here, we describe how the Trypa-NO! Partnership is using novel and classical tools to drive g-HAT elimination in an integrated approach, progress made, lessons learnt, and future directions.

Mots-clés Agrovoc : Trypanosoma gambiense, Trypanosoma brucei, trypanosomose africaine, contrôle de maladies, éradication des maladies, vecteur de maladie, Glossina palpalis

Mots-clés géographiques Agrovoc : Afrique

Mots-clés libres : Glossina, Trypanosoma, Neglected tropical diseases

Classification Agris : L72 - Organismes nuisibles des animaux
L73 - Maladies des animaux
S50 - Santé humaine

Champ stratégique Cirad : CTS 4 (2019-) - Santé des plantes, des animaux et des écosystèmes

Auteurs et affiliations

• Ndung'u Joseph Mathu, Foundation for Innovative New Diagnostics (CHE) - auteur correspondant
• Boulangé Alain, CIRAD-BIOS-UMR INTERTRYP (BFA) ORCID: 0000-0002-8505-7465
• Picado Albert, Foundation for Innovative New Diagnostics (CHE)
• Mugenyi Albert, COCTU (UGA)
• Mortensen Allan, Vestergaard SA (CHE)
• Hope Andrew, Liverpool School of Tropical Medicine (GBR)
• Guihini Mollo Brahim, IRED (TCD)
• Bucheton Bruno, IRD (FRA)
• Wamboga Charles, Ministry of Health (UGA)
• Waiswa Charles, COCTU (UGA)
• Kaba Dramane, IPR (CIV)
• Matovu Enock, Makerere University (UGA)
• Courtin Fabrice, IPR (CIV)
• Garrod Gala, Liverpool School of Tropical Medicine (GBR)
• Gimonneau Geoffrey, CIRAD-BIOS-UMR INTERTRYP (BFA) ORCID: 0000-0002-0613-841X
• Bingham Georgina V., Vestergaard SA (CHE)
• Mahamat Hassane Hassane, IRED (TCD)
• Tirados Inaki, Liverpool School of Tropical Medicine (GBR)
• Saldanha Isabel, Liverpool School of Tropical Medicine (GBR)
• Kaboré Jacques, CIRDES (BFA)
• et al.

Source : Cirad-Agritrop (https://agritrop.cirad.fr/597392/)

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