Knowledge of brucellosis, health-seeking behaviour, and risk factors for Brucella infection amongst workers on cattle farms in Gauteng, South Africa

Govindasamy Krpasha, Etter Eric, Harris Bernice N., Rossouw Jennifer, Abernethy Darrell A., Thompson Peter. 2021. Knowledge of brucellosis, health-seeking behaviour, and risk factors for Brucella infection amongst workers on cattle farms in Gauteng, South Africa. Pathogens, 10 (11), n.spéc. Brucella Species and Brucella melitensis:1484, 17 p.

https://doi.org/10.3390/pathogens10111484

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Quartile : Q2, Sujet : MICROBIOLOGY

Résumé : Brucellosis in humans is under-detected and underreported in sub-Saharan Africa. Risk factors associated with Brucella infection and health seeking behaviour in response to brucellosis-like symptoms, amongst cattle farm workers and veterinary officials in South Africa, are unknown. Farm workers and veterinary officials (N = 230) were screened for brucellosis using commercial Rose Bengal Test (RBT®), IgM Enzyme-linked Immunoassay (ELISA)®, IgG ELISA® and the BrucellaCapt® test. Knowledge of brucellosis and risk factors for exposure to Brucella were also investigated. Seroprevalence varied according to test used: 10.1% (RBT®), 20.9% (IgG ELISA®) and 6.5% (BrucellaCapt®). Only 22.2% (6/27) of veterinary officials opt to visit a clinic, doctor, or hospital in response to self-experienced brucellosis-like symptoms, compared to 74.9% (152/203) of farm workers (p < 0.001). Of the BrucellaCapt® seropositive participants, 53% (7/15) did not visit a clinic in response to brucellosis-like symptoms. Weak evidence of an association between the handling of afterbirth or placenta and infection of a short evolution (RBT®, IgM ELISA® and IgG ELISA® seropositive) was found (OR = 8.9, 95% CI: 1.0–81.1, p = 0.052), and strong evidence of an association between this outcome and the slaughter of cattle (OR = 5.3, 95% CI: 1.4–19.6, p = 0.013). There was strong evidence of a positive association between inactive/resolved infection and veterinary officials vs. farm workers exposed to seropositive herds (OR = 7.0, 95% CI: 2.4–20.2, p < 0.001), with a simultaneous negative association with the handling of afterbirth or placenta (OR = 3.9, 95% CI: 1.3–11.3, p = 0.012). Findings suggest a proportion of undetected clinical cases of brucellosis amongst workers on cattle farms in Gauteng.

Mots-clés Agrovoc : surveillance épidémiologique, brucellose, maladie de l'homme, bovin, transmission des maladies, travailleur agricole, Enquête pathologique, facteur de risque

Mots-clés géographiques Agrovoc : Afrique du Sud

Mots-clés libres : Bovine, Brucellosis, B. abortus, Human, Brucella, South Africa, RBT, IgG Elisa, IgM Elisa, BrucellaCap

Classification Agris : S50 - Santé humaine
L73 - Maladies des animaux

Champ stratégique Cirad : CTS 4 (2019-) - Santé des plantes, des animaux et des écosystèmes

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