Phylogenetic evidence for a clade of tick-associated trypanosomes

Koual Rachid, Buysse Marie, Grillet Justine, Binetruy Florian, Ouass Sofian, Sprong Hein, Duhayon Maxime, Boulanger Nathalie, Jourdain Frédéric, Alafaci Aurélien, Verdonck Julien, Verheyden Hélène, Rispe Claude, Plantard Olivier, Duron Olivier. 2023. Phylogenetic evidence for a clade of tick-associated trypanosomes. Parasites and Vectors, 16:3, 13 p.

https://doi.org/10.1186/s13071-022-05622-y

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Url - jeu de données - Entrepôt autre : https://www.ncbi.nlm.nih.gov/nuccore/OQ025404 / Url - jeu de données - Entrepôt autre : https://www.ncbi.nlm.nih.gov/nuccore/OQ025411

Résumé : Background: Trypanosomes are protozoan parasites of vertebrates that are of medical and veterinary concern. A variety of blood-feeding invertebrates have been identified as vectors, but the role of ticks in trypanosome transmission remains unclear. Methods: In this study, we undertook extensive molecular screening for the presence and genetic diversity of trypanosomes in field ticks. Results: Examination of 1089 specimens belonging to 28 tick species from Europe and South America led to the identification of two new trypanosome strains. The prevalence may be as high as 4% in tick species such as the castor bean tick Ixodes ricinus, but we found no evidence of transovarial transmission. Further phylogenetic analyses based on 18S rRNA, EF1-α, hsp60 and hsp85 gene sequences revealed that different tick species, originating from different continents, often harbour phylogenetically related trypanosome strains and species. Most tick-associated trypanosomes cluster in a monophyletic clade, the Trypanosoma pestanai clade, distinct from clades of trypanosomes associated with transmission by other blood-feeding invertebrates. Conclusions: These observations suggest that ticks may be specific arthropod hosts for trypanosomes of the T. pestanai clade. Phylogenetic analyses provide further evidence that ticks may transmit these trypanosomes to a diversity of mammal species (including placental and marsupial species) on most continents.

Mots-clés Agrovoc : Trypanosoma, Ixodes ricinus

Mots-clés complémentaires : Trypanosoma pestanai

Mots-clés libres : Trypanosoma pestanai, Trypanosome specificity, Amblyomma, Ixodes ricinus

Classification Agris : L72 - Organismes nuisibles des animaux

Champ stratégique Cirad : CTS 4 (2019-) - Santé des plantes, des animaux et des écosystèmes

Agences de financement hors UE : Agence Nationale de la Recherche

Projets sur financement : (FRA) CEnter of the study of Biodiversity in Amazonia, (FRA) Mediterranean Center for Environment and Biodiversity

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