Genomic characterization of peste des petits ruminants vaccine seed “45G37/35-k”, Russia

Kwiatek Olivier, Libeau Geneviève, Guendouz Samia, Corbanini Chloé, Gogin Andrey, Lunitsin Andrey, Sindryakova Irina, Koblasov Denis, Bataille Arnaud. 2022. Genomic characterization of peste des petits ruminants vaccine seed “45G37/35-k”, Russia. Veterinary Research, 53 (1):79, 5 p.

Url - jeu de données - Entrepôt autre : https://figshare.com/articles/journal_contribution/Additional_file_1_of_Genomic_characterization_of_peste_des_petits_ruminants_vaccine_seed_45G37_35-k_Russia/21303123 / Url - jeu de données - Entrepôt autre : https://www.ncbi.nlm.nih.gov/nuccore/ON207131

Résumé : Production of peste des petits ruminants (PPR) vaccines in Russia is based on two attenuated virus strains (“45G37/35-k” and “ARRIAH”) of common origin. Here, the identity of the strain PPRV/45G37/35-k was investigated using a full genome, Illumina deep sequencing approach. Phylogenomic analysis showed that PPRV/45G37/35-k belongs to the same lineage as the widely used PPRV vaccine strain Nigeria/75/1 (lineage II). However, 248 nucleotide differences separate the genomes of these vaccine strains, indicating that the PPRV vaccine strains produced in Russia are new strains not yet recognised by the World Organization for Animal Health (WOAH). Detailed information on the safety and efficacy of these vaccines should be provided to the WOAH before further national and international distribution.

Mots-clés Agrovoc : peste des petits ruminants

Mots-clés géographiques Agrovoc : Fédération de Russie

Classification Agris : L70 - Sciences et hygiène vétérinaires - Considérations générales
L75 - Pharmacologie et toxicologie

Champ stratégique Cirad : CTS 4 (2019-) - Santé des plantes, des animaux et des écosystèmes

Agences de financement hors UE : World Organisation for Animal Health, Food and Agriculture Organization

Auteurs et affiliations

• Kwiatek Olivier, CIRAD-BIOS-UMR ASTRE (FRA)
• Libeau Geneviève, CIRAD-BIOS-UMR ASTRE (FRA)
• Guendouz Samia, CIRAD-BIOS-UMR ASTRE (FRA)
• Corbanini Chloé, CIRAD-PERSYST-UPR HortSys (MTQ)
• Gogin Andrey, Federal Research Center for Virology and Microbiology (RUS)
• Lunitsin Andrey, Federal Research Center for Virology and Microbiology (RUS)
• Sindryakova Irina, Federal Research Center for Virology and Microbiology (RUS)
• Koblasov Denis, Federal Research Center for Virology and Microbiology (RUS)
• Bataille Arnaud, CIRAD-BIOS-UMR ASTRE (FRA) ORCID: 0000-0002-3508-2144 - auteur correspondant

Source : Cirad-Agritrop (https://agritrop.cirad.fr/604080/)

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