Peste des petits ruminants screening and diagnostic tests in African wildlife in the context of rinderpest eradication (1994-2007)

Grosbois Vladimir, Kwiatek Olivier, Gaidet Nicolas, Chardonnet Philippe, Chardonnet Bertrand, Bataille Arnaud, Parida Satya, Roger François, Kock Richard, Libeau Geneviève, Caron Alexandre. 2023. Peste des petits ruminants screening and diagnostic tests in African wildlife in the context of rinderpest eradication (1994-2007). Transboundary and Emerging Diseases, 2023:5542497, 17 p.

Résumé : Peste des petits ruminants (PPR) virus causes a major disease in domestic and wild small ruminants. Understanding the role of wildlife in PPR virus ecology is important for PPR control and its eradication targeted worldwide in 2030. Developing diagnostic tools that provide reliable data for PPR detection in wildlife will help monitor wild populations for PPR and support the eradication program. We analyze a continental-scale dataset from African free-ranging wild ungulates (n = 2570) collected between 1994 and 2007. A Bayesian model estimated the performance of ELISA tests against PPR and rinderpest and their prevalence in African buffalo. The H- and N-ELISA tests used, not initially developed for wildlife, showed poor sensitivities for the detection of PPR antibodies in African buffalo. The estimations of PPR antibody prevalence derived from the results of these tests for animals presumably not exposed or potentially exposed to PPR were uncertain. Thus, poor performances of these PPR serological tests in wildlife would not allow robust estimations of PPR antibody prevalence in African buffalo and would be extremely speculative in non-buffalo wild ungulate species. We recommend that current and new tests be validated for wildlife hosts to provide sufficient sensitivity and specificity of detection and a diagnostic protocol be developed for PPR wildlife research.

Mots-clés Agrovoc : peste des petits ruminants, épidémiologie, éradication des maladies

Mots-clés géographiques Agrovoc : Afrique

Mots-clés libres : Peste des petits ruminants, Wildlife, Peste bovine, Afrique

Classification Agris : L73 - Maladies des animaux

Champ stratégique Cirad : CTS 4 (2019-) - Santé des plantes, des animaux et des écosystèmes

Agences de financement européennes : European Commission

Projets sur financement : (EU) ANIHWA CALL1:Improved Understanding of Epidemiology of PPR

Auteurs et affiliations

• Grosbois Vladimir, CIRAD-BIOS-UMR ASTRE (ZWE) ORCID: 0000-0003-1835-1434
• Kwiatek Olivier, CIRAD-BIOS-UMR ASTRE (FRA)
• Gaidet Nicolas, CIRAD-ES-UMR SENS (FRA)
• Chardonnet Philippe, IUCN (CHE)
• Chardonnet Bertrand
• Bataille Arnaud, CIRAD-BIOS-UMR ASTRE (FRA)
• Parida Satya, FAO (ITA)
• Roger François, CIRAD-BIOS-UMR ASTRE (FRA) ORCID: 0000-0002-1573-6833
• Kock Richard, Royal Veterinary College (GBR)
• Libeau Geneviève, CIRAD-BIOS-UMR ASTRE (FRA)
• Caron Alexandre, CIRAD-BIOS-UMR ASTRE (MOZ) ORCID: 0000-0002-5213-3273 - auteur correspondant

Source : Cirad-Agritrop (https://agritrop.cirad.fr/605115/)

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