PPR Control in a Sahelian Setting: What vaccination strategy for Mauritania?

El Arbi Ahmed Salem, Kane Yaghouba, Metras Raphaëlle, Hammami Pachka, Ciss Mamadou, Beye Assane, Lancelot Renaud, Diallo Adama, Apolloni Andrea. 2019. PPR Control in a Sahelian Setting: What vaccination strategy for Mauritania?. Frontiers in Veterinary Science, 6:242, 18 p.

Quartile : Q1, Sujet : VETERINARY SCIENCES

Résumé : Peste des Petits Ruminants (PPR) is a viral disease affecting domestic and small wild ruminants. Endemic in large parts of the world, PPR causes severe damages to animal production and household economies. In 2015, FAO and OIE launched a global eradication program (GCSE) based on vaccination campaigns. The success of GCSE shall depend on the implementation of vaccination campaigns, accounting for husbandry practices, mobility and the periodicity of small ruminants' population renewal. In Mauritania, PPR outbreaks occur annually despite ongoing annual vaccination campaigns since 2008. Here, we developed a mathematical model to assess the impact of four vaccination strategies (including the GSCE one), the importance of their timing of implementation and the usefulness of individual animal identification on the reduction of PPR burden. The model was calibrated on data collected through ad-hoc surveys about demographic dynamics, disease impact, and national seroprevalence using Monte Carlo Markov Chain procedure. Numerical simulations were used to estimate the number of averted deaths over the next 12 years. The model results showed that the GSCE strategy prevented the largest number of deaths (9.2 million vs. 6.2 for random strategy) and provided one of the highest economic returns among all strategies (Benefit-Cost Ratio around 16 vs. 7 for random strategy). According to its current cost, identification would be a viable investment that could reduce the number of vaccine doses to distribute by 20–60%. Whilst the implementation of the identification system is crucial for PPR control, its success depends also on a coordinated approach at the regional level.

Mots-clés Agrovoc : peste des petits ruminants, vaccination, méthode statistique, dynamique des populations

Mots-clés géographiques Agrovoc : Mauritanie

Mots-clés libres : PPR, West Africa, Mathematical modeling, Vaccination, Cost-benefit analysis, Global strategy for control and eradication (GSCE)

Classification Agris : L73 - Maladies des animaux
U10 - Informatique, mathématiques et statistiques

Champ stratégique Cirad : CTS 4 (2019-) - Santé des plantes, des animaux et des écosystèmes

Auteurs et affiliations

• El Arbi Ahmed Salem, Ministère de l'élevage (Mauritanie) (MRT)
• Kane Yaghouba, EISMV (SEN)
• Metras Raphaëlle, CIRAD-BIOS-UMR ASTRE (FRA)
• Hammami Pachka, CIRAD-BIOS-UMR ASTRE (FRA)
• Ciss Mamadou, ISRA (SEN)
• Beye Assane, University Cheikh Anta Diop of Dakar (SEN)
• Lancelot Renaud, CIRAD-BIOS-UMR ASTRE (FRA)
• Diallo Adama, CIRAD-BIOS-UMR ASTRE (SEN)
• Apolloni Andrea, CIRAD-BIOS-UMR ASTRE (SEN) ORCID: 0000-0002-0228-2086 - auteur correspondant

Source : Cirad-Agritrop (https://agritrop.cirad.fr/593696/)

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