Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa

Sichewo Petronillah Rudo, Hlokwe Tiny, Etter Eric, Michel Anita Luise. 2020. Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa. BMC Microbiology, 20:49, 9 p.

Quartile : Q2, Sujet : MICROBIOLOGY

Résumé : Background: Bovine tuberculosis (bTB) affects cattle and wildlife in South Africa with the African buffalo (Syncerus caffer) as the principal maintenance host. The presence of a wildlife maintenance host at the wildlife/livestock interface acting as spill-over host makes it much more challenging to control and eradicate bTB in cattle. Spoligotyping and mycobacterial interspersed repetitive unit-variable number of tandem repeat (MIRU-VNTR) genotyping methods were performed to investigate the genetic diversity of Mycobacterium bovis (M. bovis) isolates from cattle and wildlife, their distribution and transmission at the wildlife/livestock interface in northern Kwa-Zulu Natal (KZN), South Africa. Results: SB0130 was identified as the dominant spoligotype pattern at this wildlife/livestock interface, while VNTR typing revealed a total of 29 VNTR profiles (strains) in the KZN province signifying high genetic variability. The detection of 5 VNTR profiles shared between cattle and buffalo suggests M. bovis transmission between species. MIRU-VNTR confirmed co-infection in one cow with three strains of M. bovis that differed at a single locus, with 2 being shared with buffalo, implying pathogen introduction from most probably unrelated wildlife sources. Conclusion: Our findings highlight inter and intra species transmission of bTB at the wildlife/livestock interface and the need for the implementation of adequate bTB control measures to mitigate the spread of the pathogen responsible for economic losses and a public health threat.

Mots-clés Agrovoc : Mycobacterium bovis, Syncerus caffer, tuberculose, transmission des maladies, contrôle de maladies, bétail, animal sauvage

Mots-clés géographiques Agrovoc : Afrique du Sud

Mots-clés complémentaires : Tuberculose bovine

Mots-clés libres : African buffalo, Mycobacterium bovis (M. bovis), Bovine tuberculosis, Cattle, Strains, Wildlife, Wildlife-livestock interface

Classification Agris : L73 - Maladies des animaux

Champ stratégique Cirad : CTS 4 (2019-) - Santé des plantes, des animaux et des écosystèmes

Auteurs et affiliations

• Sichewo Petronillah Rudo, University of Pretoria (ZAF) - auteur correspondant
• Hlokwe Tiny, ARC (ZAF)
• Etter Eric, CIRAD-BIOS-UMR ASTRE (ZAF)
• Michel Anita Luise, University of Pretoria (ZAF)

Source : Cirad-Agritrop (https://agritrop.cirad.fr/595300/)

Métriques

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