Fusaro Alice, Zecchin Bianca, Vrancken Bram, Abolnik Célia, Ademun Rose, Alassane Abdou, Arafa Abdelsatar, Awuni Joseph Adongo, Couacy-Hymann Emmanuel, Coulibaly M.' Bétiégué, Gaidet Nicolas, Go-Maro Emilie, Joannis Tony M., Jumbo Simon Dickmu, Minoungou Germaine, Meseko Clement, Souley Maman Moutari, Ndumu Deo Birungi, Shittu Ismaila, Twabela Augustin, Wade Abel, Wiersma Lidewij, Akpeli Yao P., Zamperin Gianpiero, Milani Adelaide, Lemey Philippe, Monne Isabella. 2019. Disentangling the role of Africa in the global spread of H5 highly pathogenic avian influenza. Nature Communications, 10:5310, 13 p.
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Url - jeu de données - Entrepôt autre : https://www.ncbi.nlm.nih.gov/nucleotide
Quartile : Outlier, Sujet : MULTIDISCIPLINARY SCIENCES
Résumé : The role of Africa in the dynamics of the global spread of a zoonotic and economically-important virus, such as the highly pathogenic avian influenza (HPAI) H5Nx of the Gs/GD lineage, remains unexplored. Here we characterise the spatiotemporal patterns of virus diffusion during three HPAI H5Nx intercontinental epidemic waves and demonstrate that Africa mainly acted as an ecological sink of the HPAI H5Nx viruses. A joint analysis of host dynamics and continuous spatial diffusion indicates that poultry trade as well as wild bird migrations have contributed to the virus spreading into Africa, with West Africa acting as a crucial hotspot for virus introduction and dissemination into the continent. We demonstrate varying paths of avian influenza incursions into Africa as well as virus spread within Africa over time, which reveal that virus expansion is a complex phenomenon, shaped by an intricate interplay between avian host ecology, virus characteristics and environmental variables.
Mots-clés Agrovoc : Influenzavirus aviaire, surveillance épidémiologique, volaille, grippe aviaire, oiseau, épidémiologie, animal sauvage, transmission des maladies, phylogénie, migration animale, épidémie, distribution géographique
Mots-clés géographiques Agrovoc : Afrique, Afrique occidentale, Afrique au sud du Sahara
Mots-clés libres : Influenza virus, Phylogenetics, Viral epidemiology, Viral transmission
Agences de financement européennes : European Commission
Agences de financement hors UE : United States Agency for International Development
Programme de financement européen : H2020
Projets sur financement : (EU) Dynamics of avian influenza in a changing world, (EU) The evolutionary dynamics of pathogen emergence and establishment: from Reservoir Detection to Outbreak Control
Auteurs et affiliations
- Fusaro Alice, Istituto zooprofilattico sperimentale delle Venezie (ITA) - auteur correspondant
- Zecchin Bianca, Istituto zooprofilattico sperimentale delle Venezie (ITA)
- Vrancken Bram, KUL (BEL)
- Abolnik Célia, University of Pretoria (ZAF)
- Ademun Rose, National Animal Disease Diagnostics and Epidemiology Centre (UGA)
- Alassane Abdou, Laboratoire central de l'élevage (NER)
- Arafa Abdelsatar, Animal Health Research Institute (EGY)
- Awuni Joseph Adongo, Accra Veterinary Laboratory (GHA)
- Couacy-Hymann Emmanuel, Laboratoire Central de Pathologie Animale (CIV)
- Coulibaly M.' Bétiégué, LANADA (CIV)
- Gaidet Nicolas, CIRAD-ES-UPR GREEN (FRA)
- Go-Maro Emilie, Laboratoire Central Vétérinaire de Lomé (TGO)
- Joannis Tony M., NVRI (NGA)
- Jumbo Simon Dickmu, LANAVET (CMR)
- Minoungou Germaine, Laboratoire National d'Elevage (BFA)
- Meseko Clement, NVRI (NGA)
- Souley Maman Moutari, LABOCEL (NER)
- Ndumu Deo Birungi, National Animal Disease Diagnostics and Epidemiology Centre (UGA)
- Shittu Ismaila, NVRI (NGA)
- Twabela Augustin, Veterinary Laboratory of Kinshasa (COD)
- Wade Abel, LANAVET (CMR)
- Wiersma Lidewij, FAO (ITA)
- Akpeli Yao P., Laboratoire Central Vétérinaire de Lomé (TGO)
- Zamperin Gianpiero, Istituto zooprofilattico sperimentale delle Venezie (ITA)
- Milani Adelaide, Istituto zooprofilattico sperimentale delle Venezie (ITA)
- Lemey Philippe, KUL (BEL)
- Monne Isabella, Istituto zooprofilattico sperimentale delle Venezie (ITA) - auteur correspondant
Source : Cirad-Agritrop (https://agritrop.cirad.fr/605039/)
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