Wide diversity of coronaviruses in frugivorous and insectivorous bat species: A pilot study in Guinea, West Africa

Lacroix Audrey, Vidal Nicole, Keita Alpha Kabinet, Thaurignac Guillaume, Esteban Amandine, De Nys Hélène, Diallo Ramadan, Toure Abdoulaye, Goumou Souana, Soumah Abdoul Karim, Povogui Moriba, Koivogui Lamine, Monemou Jean-Louis, Raulino Raisa, Nkuba Antoine, Foulongne Vincent, Delaporte Eric, Ayouba Ahidjo, Peeters Martine. 2020. Wide diversity of coronaviruses in frugivorous and insectivorous bat species: A pilot study in Guinea, West Africa. Viruses, 12 (8):855, 17 p.

Quartile : Q2, Sujet : VIROLOGY

Résumé : Zoonoses can constitute a threat for public health that can have a global importance, as seen with the current COVID-19 pandemic of severe acute respiratory syndrome coronavirus (SARS-CoV2). Bats have been recognized as an important reservoir of zoonotic coronaviruses (CoVs). In West Africa, where there is a high diversity of bat species, little is known on the circulation of CoVs in these hosts, especially at the interface with human populations. In this study, in Guinea, we tested a total of 319 bats belonging to 14 genera and six families of insectivorous and frugivorous bats across the country, for the presence of coronaviruses. We found CoVs in 35 (11%) of the tested bats—in three insectivorous bat species and five fruit bat species that were mostly captured close to human habitat. Positivity rates varied from 5.7% to 100%, depending on bat species. A wide diversity of alpha and beta coronaviruses was found across the country, including three sequences belonging to SarbeCoVs and MerbeCoVs subgenera known to harbor highly pathogenic human coronaviruses. Our findings suggest that CoVs are widely spread in West Africa and their circulation should be assessed to evaluate the risk of exposure of potential zoonotic CoVs to humans.

Mots-clés Agrovoc : Chiroptera, coronavirus 2 du syndrome respiratoire aigu sévère, zoonose, covid-19, variation génétique, transmission des maladies, santé publique, maladie infectieuse, Ebolavirus, Orthocoronavirinae

Mots-clés géographiques Agrovoc : Afrique occidentale, Guinée, Sénégal, Ghana, Afrique

Mots-clés libres : Bat, Coronavirus, Guinea, Virus diversity, Africa

Agences de financement européennes : European Commission

Agences de financement hors UE : Institut National de la Santé et de la Recherche Médicale, Institut de Recherche pour le Développement, Agence Nationale de Recherches sur le Sida et les Hépatites Virales, Agence Nationale de la Recherche

Projets sur financement : (FRA) Ebola Task Force/REACTing, (EU) EBO-SURSY, (FRA) MUSE

Auteurs et affiliations

• Lacroix Audrey, IRD (FRA)
• Vidal Nicole, IRD (FRA)
• Keita Alpha Kabinet, IRD (FRA)
• Thaurignac Guillaume, IRD (FRA)
• Esteban Amandine, IRD (FRA)
• De Nys Hélène, CIRAD-BIOS-UMR ASTRE (ZWE) ORCID: 0000-0002-2942-4531
• Diallo Ramadan, Ministère de l'Elevage et des Productions Animales (Guinée) (GIN)
• Toure Abdoulaye, Institut national de santé publique (GIN)
• Goumou Souana, UGANC (GIN)
• Soumah Abdoul Karim, UGANC (GIN)
• Povogui Moriba, UGANC (GIN)
• Koivogui Lamine, UGANC (GIN)
• Monemou Jean-Louis, UGANC (GIN)
• Raulino Raisa, UGANC (GIN)
• Nkuba Antoine, IRD (FRA)
• Foulongne Vincent, CHU Montpellier (FRA)
• Delaporte Eric, IRD (FRA)
• Ayouba Ahidjo, IRD (FRA) - auteur correspondant
• Peeters Martine, IRD (FRA) - auteur correspondant

Source : Cirad-Agritrop (https://agritrop.cirad.fr/608827/)

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