Agritrop
Home

Phytosterol vehicles used in a functional product modify carotenoid/cholesterol bioaccessibility and uptake by Caco-2 cells

Gies Magali, Servent Adrien, Borel Patrick, Dhuique-Mayer Claudie. 2020. Phytosterol vehicles used in a functional product modify carotenoid/cholesterol bioaccessibility and uptake by Caco-2 cells. Journal of Functional Foods, 68:103920, 8 p.

Journal article ; Article de recherche ; Article de revue à facteur d'impact
[img] Version Online first - Anglais
Access restricted to CIRAD agents
Use under authorization by the author or CIRAD.
595453.pdf

Télécharger (285kB) | Request a copy

Abstract : Functional foods containing dispersible phytosterols (DPs) are recommended to reduce cholesterol absorption in humans. However, only a few studies have been conducted on the effect of DP vehicles on carotenoid bioaccessibility and uptake by intestinal cells. On a previously developed fermented maize product containing both DPs and carotenoids, we aim to evaluate the effect of DPs encapsulated by maltodextrin on the carotenoid/phytosterol/cholesterol interactions during gastro-duodenal digestion. Thanks to maltodextrin properties, β-carotene and lycopene bioaccessibilities were significantly improved by 40.2 ± 1.4% while that of β-cryptoxanthin decreased by 14 ± 0.1%. Additionally, the presence of DPs reduced the cholesterol micellarization by 51.8 ± 4.2%. Despite a slight decrease in carotenoid uptake caused by the DP vehicle, related to micelle size, an inhibition of cholesterol accumulation by Caco-2 cells was observed. These results highlighted the key role of maltodextrin as a vehicle of DPs on carotenoid and cholesterol absorption.

Mots-clés Agrovoc : Phytostérol, Maltodextrine, Absorption digestive, Cholestérol, Carotène, Lycopène, Caroténoïde

Mots-clés libres : Dispersible phytosterols, Maltodextrin, Carotenes, Xanthophylls, Bioaccessibility, Caco-2 cells

Classification Agris : S20 - Physiology of human nutrition

Champ stratégique Cirad : CTS 3 (2019-) - Systèmes alimentaires

Auteurs et affiliations

  • Gies Magali, CIRAD-PERSYST-UMR Qualisud (FRA)
  • Servent Adrien, CIRAD-PERSYST-UMR Qualisud (FRA)
  • Borel Patrick, INSERM (FRA)
  • Dhuique-Mayer Claudie, CIRAD-PERSYST-UMR Qualisud (FRA) - auteur correspondant

Source : Cirad-Agritrop (https://agritrop.cirad.fr/595453/)

View Item (staff only) View Item (staff only)

[ Page générée et mise en cache le 2020-10-13 ]