Alhaj Omar A., Abodoleh Ghaida, Abu Jadayil Seham, Irshaid Nagham, Mehta Bhavbhuti M., Faye Bernard, Jahrami Haitham A.. 2024. A systematic review and meta-analysis of the antihypertensive effects of camel milk hydrolysates. International Journal of Dairy Technology, 77 (4) : 1029-1043.
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Résumé : This meta-analysis aimed to estimate the antihypertensive effects of camel milk (CM) hydrolysates, including the variation in camel milk hydrolysates among different hydrolysis types, incubation times, and experimental designs. The antihypertensive effect of CM hydrolysate is expressed as the percentage of angiotensin-converting enzyme (ACE) activity or IC50 value provided in μg/ml, corresponding to the 50% maximum inhibitory concentration. The greatest random effect of antihypertensive agents (IC50 μg/mL) in vitro was 122.9 at incubation time of 144–216 h. Moreover, the greatest random effect of ACE % in vitro was 76.7 after 48 h of incubation. In vivo, the random effect of ACE % was 62.7, and the incubation time was 0.16–6 h. The antihypertensive effect of CM hydrolysate depends on several factors, including hydrolysis type, incubation time, and experimental design.
Mots-clés Agrovoc : lait de chamelle, dromadaire, expérimentation in vitro, chameau, hydrolyse, expérimentation in vivo, antihypertenseur, enzyme, pression sanguine, hypertension
Mots-clés libres : Camel milk hydrolysates, Hydrolysis type, Incubation time, Experimental design, Antihypertensive effect
Auteurs et affiliations
- Alhaj Omar A., University of Petra (JOR) - auteur correspondant
- Abodoleh Ghaida, University of Petra (JOR)
- Abu Jadayil Seham, University of Petra (JOR)
- Irshaid Nagham, University of Petra (JOR)
- Mehta Bhavbhuti M., Kamdhenu University (IND)
- Faye Bernard, CIRAD-ES-UMR SELMET (FRA)
- Jahrami Haitham A., Arabian Gulf University (BHR)
Source : Cirad-Agritrop (https://agritrop.cirad.fr/610895/)
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