Repeated gain and loss of a single gene modulates the evolution of vascular plant pathogen lifestyles

Gluck-Thaler E., Cerutti Aude, Pérez-Quintero Alvaro L., Butchacas Jules, Roman-Reyna Verónica, Madhavan Vishnu Narayanan, Shantharaj Deepak, Merfa Marcus V., Pesce Céline, Jauneau Alain, Vancheva T., Lang Jillian M., Allen Caitilyn, Verdier Valérie, Gagnevin Lionel, Szurek Boris, Beckham Gregg T., De La Fuente Leonardo, Patel Hitendra Kumar, Sonti Ramesh V., Bragard Claude, Leach Jan E., Noel Laurent D., Slot J., Koebnik Ralf, Jacobs Jonathan M.. 2020. Repeated gain and loss of a single gene modulates the evolution of vascular plant pathogen lifestyles. Science Advances, 6 (46), 10 p.

Quartile : Outlier, Sujet : MULTIDISCIPLINARY SCIENCES

Résumé : Vascular plant pathogens travel long distances through host veins, leading to life-threatening, systemic infections. In contrast, nonvascular pathogens remain restricted to infection sites, triggering localized symptom development. The contrasting features of vascular and nonvascular diseases suggest distinct etiologies, but the basis for each remains unclear. Here, we show that the hydrolase CbsA acts as a phenotypic switch between vascular and nonvascular plant pathogenesis. cbsA was enriched in genomes of vascular phytopathogenic bacteria in the family Xanthomonadaceae and absent in most nonvascular species. CbsA expression allowed nonvascular Xanthomonas to cause vascular blight, while cbsA mutagenesis resulted in reduction of vascular or enhanced nonvascular symptom development. Phylogenetic hypothesis testing further revealed that cbsA was lost in multiple nonvascular lineages and more recently gained by some vascular subgroups, suggesting that vascular pathogenesis is ancestral. Our results overall demonstrate how the gain and loss of single loci can facilitate the evolution of complex ecological traits. evolution of complex ecological traits.

Mots-clés Agrovoc : phylogénie, relation hôte pathogène, Oryza sativa, génome, maladie des plantes, agent pathogène, évolution, plante hôte, Xanthomonas, variation génétique

Agences de financement hors UE : National Science Foundation, U.S. Department of Agriculture, European Cooperation in Science and Technology, University Grants Commission of India, Ministère de l'Education Nationale, de l'Enseignement Supérieur et de la Recherche, U.S. Department of Energy

Projets sur financement : (FRA) Production, perception et transport de phytohormones par les champignons mycorhiziens à arbuscules, (FRA) Towards a Unified theory of biotic Interactions: the roLe of environmental

Auteurs et affiliations

• Gluck-Thaler E., Ohio State University (USA)
• Cerutti Aude, INRAE (FRA)
• Pérez-Quintero Alvaro L., IRD (FRA)
• Butchacas Jules, Ohio State University (USA)
• Roman-Reyna Verónica, Ohio State University (USA)
• Madhavan Vishnu Narayanan, CSIR (IND)
• Shantharaj Deepak, Auburn University (USA)
• Merfa Marcus V., Auburn University (USA)
• Pesce Céline, IRD (FRA)
• Jauneau Alain, CNRS (FRA)
• Vancheva T., UCL (BEL)
• Lang Jillian M., Colorado State University (USA)
• Allen Caitilyn, University of Wisconsin (USA)
• Verdier Valérie, IRD (FRA)
• Gagnevin Lionel, CIRAD-BIOS-UMR IPME (FRA)
• Szurek Boris, IRD (FRA)
• Beckham Gregg T., National Renewable Energy Laboratory (USA)
• De La Fuente Leonardo, Auburn University (USA)
• Patel Hitendra Kumar, CSIR (IND)
• Sonti Ramesh V., CSIR (IND)
• Bragard Claude, UCL (BEL)
• Leach Jan E., Colorado State University (USA)
• Noel Laurent D., INRAE (FRA)
• Slot J., Ohio State University (USA)
• Koebnik Ralf, IRD (FRA)
• Jacobs Jonathan M., IRD (FRA)

Source : Cirad-Agritrop (https://agritrop.cirad.fr/605398/)

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